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doi:10.1056/NEJMoa1301467 Hu S, Yu Q, Wang Y, Wang M, Xia W, Zhu C

The currently offered delivery methods are: Economy Mail (economy letter - Japan Post), Air Mail (registered letter - Japan Post), EMS (courier service - Japan Post) and SEA Shipping (sea parcel - Japan Post)

Using standardized literature screening, we included four randomized controlled trials (RCTs): SUSTAIN 6, PIONEER 6, FLOW, and SOUL

However, observational studies hint at possible protective effects, particularly in patients who achieve significant weight loss

Many patients report reduced appetite and increased feelings of fullness within the first week of treatment, though individual experiences vary considerably