The fact that you have been on a stable dose without allodynia symptoms is reassuring
doi: 10.1186/s13000-016-0475-5 181 WoodSMGillAJBrodskyASLuSFriedmanKKarashchukGet al
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493 In terms of chemotherapy sensitization, lactate has been found to confer chemoresistance by increasing the expression of multidrug resistance-associated protein 1 (MRP1, encoded by ATP-binding cassette sub-family C member 1 (ABCC1)), which induces drug efflux from cells
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