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Quality by design approach for formulation, evaluation and statistical optimization of diclofenac-loaded ethosomes via transdermal route

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There were two reports each of hyperpigmentation, cheilitis, sore throat, unspecified mood change, joint pain, fatigue, cold sores, and elevated liver enzyme levels (0.9%)

References Aletaha D, Neogi T, Silman AJ et al (2010) 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

There are minimal risks of taking glutathione supplements during pregnancy, as long as the supplements are used as directed