Resistant Tapioca Dextrin (FiberSMART) FiberSMART is a digestion-resistant soluble fiber that helps feed beneficial bacteria like Bifidobacterium and Akkermansia muciniphila
Well-characterized mechanism including appetite suppression, glucose-dependent insulin secretion, and gastric emptying delay
Since they contain the same active drug component, they also share similar mechanisms of action, such as appetite suppression, decreased gastric emptying, and enhanced insulin secretion
Significantly, BBR has emerged as a widespread inhibitor of HDACs and is capable of down-regulating HDAC4, thereby enhancing epigenetic modifications through increased histone acetylation (Kandasamy et al., 2023)
Oxidative stress, driven in part by metabolite and proteome alterations, appears to play a central role in the pathology of ME/CFS, GWS, and FM