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Research is clear that combining GLP-1 medications with structured exercise preserves muscle, improves metabolic outcomes, and makes long-term weight maintenance more likely after the medication is discontinued

Among CagriSema-treated participants, 73.5% achieved HbA1c of 6.5% or below compared to 15.9% with placebo, demonstrating remarkable dual efficacy for both weight and glycemic endpoints

For the detection of the reference gene GAPDH sense 5-TCA AGG CTG AGA ACG GGA AG-3 and antisense 5-CGC CCC ACT TGA TTT TGG AG-3 primers were used

Intermittent fasting promotes adipocyte mitochondrial fusion through Sirt3-mediated deacetylation of Mdh2

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