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Elevated intra-articular iron levels and altered expression of ferroptosis-related molecules such as ACSL4 and GPX4 have been associated with the severity of joint pain, cartilage damage, and functional decline ( In summary, ferroptosis is a shared pathological mechanism across multiple joint tissues in OA

Muscle, especially axial muscle, is essential for posture, physical function and overall well-being

The membranes were blocked in 5% non-fat milk and incubated overnight at 4 degrees Celsius, with primary antibodies

both processes govern ferroptosis in renal I/R injury

December 2025 (Complete) TRIUMPH-4 Phase 3 topline results released