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Pharmacologically, cysteine availability can be augmented by N-acetylcysteine (NAC), which is deacetylated intracellularly to supply cysteine for GSH synthesis 22

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When people stop taking them, they are essentially taking their foot off the brake, Field said in a statement provided to the Science Media Centre

While these mechanisms make them highly effective, they also predispose patients to gastrointestinal adverse effects, such as nausea, vomiting, abdominal discomfort, and constipation