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It didnt preserve muscle ..patients lost 3kg over the first 7 months and lost little muscle mass thereafter...about 2.5% of starting body weight..it doesn't show if they followed a designated exercise routine ..but I would assume so ..more potent glp1R agonists might elicit higher rates of muscle loss..TBD

The decision to take a prescription that has an FDA black box warning should not be taken lightly and should be discussed with your healthcare provider

Tirzepatide, a dual agonist for GLP-1 and GIP receptors, effectively promotes weight loss and improves metabolic parameters by influencing insulin secretion, appetite regulation, and gastric emptying

Semaglutide and Tirzepatide are prescribed weight loss medications that are administered under the supervision of a healthcare professional

For obesity alone, you must use FDA-approved Wegovy, not off-label diabetes drugs