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J Neurosci 36(23):61656174 Jander S, Schroeter M, Peters O, Witte OW, Stoll G (2001) Cortical spreading depression induces proinflammatory cytokine gene expression in the rat brain

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Intramuscular injection is sometimes discussed in the context of localized injury research, though controlled data comparing routes are absent

No wonder they ate less, but evidently the degree of gastrointestinal discomfort did not correlate with how much less they ate

If plain water is unappealing, try infusing it with fruit slices or a splash of lemon