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Understanding GLP-1s for diabetes, weight loss, and beyond, April 14, 2025 Harvard Health, Trying to lose weight
Reports of adverse events and dosing errors The FDA has received hundreds of adverse event reports linked to compounded versions of semaglutide and tirzepatide, including cases involving nausea, vomiting, abdominal pain, and other gastrointestinal symptoms
Any effect on GLP-1 appears to be indirect and secondary, with the evidence remaining limited and inconsistent
Clinical data supports that sustained GLP-1 therapy maintains weight loss, improves cardiovascular outcomes, and prevents metabolic deterioration far better than stopping treatment
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