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77 However, there is currently no histological evaluation data confirming these findings for EX-BID

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Centrally, these medications may affect brain appetite centers through multiple pathways, including signaling via vagal afferents and action on circumventricular organs (brain regions with a more permeable blood-brain barrier)

Patients also report reduced cravings for unhealthy foods, helping them avoid binging or indulging in processed snacks

Such studies are inherently susceptible to confounding by socioeconomic status, access to healthcare, reimbursement policies, and patient adherence, all of which may significantly impact treatment continuation and metabolic outcomes