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This syndrome has been reported to be more likely if the patient has abnormal kidney function.9 Although there is some significant debate on this point10, it is generally agreed that patients with abnormal kidney function should start allopurinol at low doses and build up, to ensure that the allopurinol is effectively excreted

Medvidovic-Grubisic et al., 2017))

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Quercetin and the related flavonoid fisetin occur in foods, quercetin in onions, capers, and apples and fisetin in strawberries, at amounts far below the trial doses, and whether food-level intake does anything for senescent cells has not been tested

Hunter et al., 2011