[20] [7] This conversion is illustrated by the reduction of peroxides (via the sulfenate as an intermediate): GSH + R 2 O 2 GSOR + ROH GSOR + GSH GSSG + ROH Net reaction: 2 GSH + R 2 O 2 GSSG + 2 ROH (R = H, alkyl) and with free radicals, forming glutathionyl radicals (GS ) that may dimerize to disulfide: GSH + R RH + GS 1/2 GSSG Thiyl radicals (such as glutathionyl radicals) are themselves oxidizing species in biology, with a single-electron reduction potential sufficient for oxidation of nucleic acids, proteins and polyunsaturated lipids
Effects on Neurotransmitters Although the primary mechanism of DIHEXA focuses on BDNF pathways, activation of these pathways may secondarily affect the levels and function of certain neurotransmitters, such as acetylcholine, dopamine, and serotonin
Shippenburg T, Bals-Kubik R
Some marketing claims (e.g., FDA-approved for weight loss) may be misleading
Potential Hair Growth Applications Emerging research suggests GHK-Cu may support hair growth by enlarging hair follicles and extending the anagen phase