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During ovulation, ROS are produced within the follicles, however, the excessive production of ROS may increase the risk for poor oocyte quality since oxidative stimulation promotes oocyte maturation and wall rupture within the follicle [390]

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Ashley CE, Carnes EC, Phillips GK, Durfee PN, Buley MD, Lino CA, Padilla DP, Phillips B, Carter MB, Willman CL, Brinker CJ, Caldeira Jdo C, Chackerian B, Wharton W, Peabody DS (2011) Cell-specific delivery of diverse cargos by bacteriophage MS2 virus-like particles