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Moreover, tumor-derived exosomes are able to promote cancer cell migration and metastasis, containing various kinds of integrin, such as exosomal integrins v 6 for prostate cancer (Carmine et al., 2015), 6 4 and 6 1 for lung cancer, and v 5 for liver cancer metastasis (Hoshino et al., 2015)

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Finally, by increasing the affinity of lipoprotein (a) for fibrin, homocysteine would inhibit the conversion of plasminogen into plasmin on the fibrin surface (Harpel et al, 1992

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