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The metabolic byproducts produced by bacteria, such as SCFAs, enhance the release of natural GLP-1, while GLP-1RAs alter signaling pathways, acid responses, immune reactions, and the composition of gut microorganisms, leading to increasingly robust therapeutic feedback mechanisms [108,109]

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Researchers aimed to investigate the safety and efficacy of liraglutide, a glucagon-like peptide 1 receptor agonist, in patients with bile acid diarrhea, which is often underdiagnosed and estimated to affect 1% to 2% of the general population