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TGR was also identified as a multifunctional oxidoreductase with a remarkably wide substrate specificity, capable of directly reducing peroxides, selenium-containing compounds, and several important low-molecular-weight antioxidants, as well as Trx, DTNB, GSSG, and GSH-HED

Eventually, 2 mL of Folin-phenol reagent were added, and absorbance was measured at 760 nm after 10 min

In sum, regular intake of glutathione has profound benefits for cellular functioning and maintaining overall wellbeing

After knockdown the GPX4 gene in epithelial cells, the researchers found that NO inhibits ferroptosis in epithelial cells even when GPX4 is deficient

Acetaminophen-induced liver injury: Implications for temporal homeostasis of lipid metabolism and eicosanoid signaling pathway