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Mechanisms include ATP sensitive K + channel closure, facilitation of VDCCs opening, inhibiting membrane repolarization via Kv channels and Ca 2+ -induced Ca 2+ release from cytoplasmic storage sites 9,10,11,12,13,14

Comp Biochem Phys A 260:111038 Chen Q, Wang C, Sun Y, Chen Y, Chen S, Han T, Wang J (2023) Oxidative stress caused by excessive substitution of fish meal with fermented soybean meal in largemouth bass ( Micropterus salmoides ) diet affecting glutathione metabolism

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Alongside their weight-loss effects by inhibiting appetite, GLP-1 receptor agonists also lead to reductions in lean body mass, including muscle and supportive fat pads, which can result in unintended effects: hollowing of the face, softening of the jawline, loss of core strength, or laxity in the neck and lower face

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