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doi: 10.1111/j.1464-5491.2010.03085.x 43 BettgeKKahleMAbd El AzizMSMeierJJNauckMA

Replacement effects are summarized in the first paragraph followed by our data interpretation in the second paragraph: Regression and pattern analyses revealed sequential kinetics for all mutants with an apparent common intersection point at the x axis (Supplementary Fig

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In this study, metformin did not alter oxidative phosphorylation or glycolysis in normal non-cancer rectal tissue biopsies, importantly suggesting that the anti-metabolic effects of metformin may be tumour tissue-specific, which supports its potential utility as a radiosensitiser in rectal cancer

Research perspective A 2001 editorial in the European Journal of Anaesthesiology described DSIP as "incredibly safe" based on the lack of lethal doses in animal studies and absence of significant side effects in human trials beyond transient symptoms