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While current treatments largely focus on symptom relief, agents such as Wnt pathway modulators (e.g., lorecivivint), ADAMTS-5 inhibitors, and nerve growth factor (NGF) antagonists like tanezumab are under investigation for their potential to alter disease progression (Jiang et al., 2021

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Accumulating evidence supports various pharmacological effects of ginger and its derivatives, including antiinflammatory, antiobesity, anti-DM, antiproliferative, antithrombotic, cardioprotective, and hepatoprotective properties (561, 575, 576)

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