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Actinobacillus actinomycetemcomitans lipopolysaccharide-mediated experimental bone loss model for aggressive periodontitis

Absolute bioavailability compares bioavailability of a drug administered via any non-intravenous route (e.g., oral, intramuscular, transdermal) to the bioavailability of the same drug given intravenously (IV)

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The Caco-2 monolayer (32) is a standard in vitro intestinal model, but it lacks a mucus layer and its tight junctions resemble those of the colon, with narrower pores (4.5 ) (33, 34) compared to the small intestine (89 ) (35) in a polarized monolayer