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Some patients do switch, and the transition can be clinically appropriate but it must be medically supervised

Thus, interventions that increase NAD+ may slow aspects of the aging trajectory, and there is great interest in methods for cellular NAD+ restoration

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Daily injections of L-carnitine in rats treated with ifosfamide resulted in less oxidative stress and kidney damage compared to treatment with ifosfamide alone (Sayed-Ahmed 2012)