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The estimation of t 1/2eff utilizes the ratio of drug exposure at steady state to drug exposure after the first dose (accumulation ratio, or R ac ), with a higher R ac indicating greater drug accumulation

Good News on Refills Once your prior authorization is approved, your subsequent monthly refills do not require a new prior authorization, as long as you remain on the same medication

To reduce skin sensitivity, ensure you rotate the injection sites, use a clean needle for each injection, and avoid injecting into areas with scars or moles

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These medications are contraindicated in pregnancy due to evidence of fetal developmental abnormalities in animal studies (4)(48)