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For example, some doctors are concerned that aspirins ability to thin the blood could cause issues for those on semaglutide, especially if they have other health conditions

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However, research about these benefits has not been published and there are no national guidelines on the best way to approach microdosing

Separately, an NHS evaluation published in the BMJ found that Second Nature achieved substantially higher weight loss than four other providers in the National Diabetes Prevention Programme

Tirzepatide achieves even larger reductions, up to 2.0 to 2.3 percentage points in clinical trials