Oral semaglutide may even lead to less nausea and vomiting than once-weekly dulaglutide and once-daily lixisenatide (two less common GLP-1 injectable medications), though its nausea profile is similar to that of injectable semaglutide
This may be related to reduced caloric intake, changes in blood sugar patterns, or direct effects on the central nervous system
In this episode of All-In, Eli Lilly CEO Dave Ricks discusses his company's development of GLP-1 drugs, which began with an unexpected discovery during diabetes treatment research and led to the creation of Monjaro
Why Gut Health Matters on GLP-1 Medication Because GLP-1 medications slow gastric emptying, bloating, nausea, and irregular digestion are common, particularly in the early weeks
Combined with the medication's effect of slowing digestion further, they are major culprits for causing or worsening nausea, vomiting, indigestion, and heartburn