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181 Advanced biophysical techniques, such as atomic force microscopy (AFM) and magnetic resonance elastography (MRE), allow researchers to measure the nanoscale mechanical properties of ACL tissue and observe changes induced by hormonal fluctuations

The resulting emulsion is then added to an aqueous extraction medium preferably containing at least one of the solvents of the blend, whereby the rate of extraction of each solvent is controlled, whereupon the biodegradable microspheres containing the pharmaceutically active agent are formed

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