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Morales Hidalgo, P., Voltas Moreso, N

Fonti scientifiche 1

Glutathione peroxidases modulate NF-B activation, which has been confirmed by the following considerations: inhibitors of cyclo-oxygenases and lipooxygenases inhibited activation of NF-B, the activity of cyclo-oxygenases depends on the hydroperoxide tone which is regulated by glutathione peroxidases, NF-B activation was inhibited in selenium-supplemented cells and facilitated in selenium deficiency

33,34 In an eight day, open-label study of palliative care patients with incurable cancer, flupirtine at 100 to 300 mg, four times daily, reduced pain scores and was associated with some reduction in opioid use