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The elevated levels of proinflammatory cytokines and chemokines such as tumour necrosis factor (TNF)-, interleukin 1 (IL-1), IL-6, IL-8 [2,7] and others indicate the cytokine storm plays a central role in the immunopathology of COVID-19, but the primary source or the exact virological mechanisms behind it have not been identified yet [8]

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ROS can exert multiple effects on the immune system, including the activation and interaction of immune cells, host defense, and immune suppression 150