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Eventually, GABA is removed from the system by converting it into succinate, which is then used in the Krebs cycle in the mitochondria to make ATP.[ref] The enzyme succinic semialdehyde dehydrogenase ( ALDH5A1 gene) is needed to convert GABA into succinate.[ref] Rare genetic mutations in the ALDH5A1 gene cause succinic semialdehyde dehydrogenase deficiency, which decreases the breakdown of GABA

Moreover, people with Sjgrens syndrome are six times more likely to develop B12 deficiency than people who dont suffer from the condition

For example, for some patients with skin neuropathy accompanied by dry and rough skin, the moisturizing ingredients in the cream can moisturize the skin and alleviate skin discomfort