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My brain went from Dont eat that cookie to Dont eat anything. Doctors are now seeing cases of: Binge eating (overeating followed by guilt) Orthorexia (unhealthy obsession with clean eating) Food avoidance so severe it mimics anorexia Why does this happen? wonders Dr

The substitution of Ala8 in GLP-1 by Gly8 in exendin-4 contributes to enhanced DPP-4 resistance ( Interestingly, until now, primarily long-chain peptides with 3339 amino acids have been developed as GLP-1RAs, which also carry a cost burden

10.1089/wound.2021.0026 115 SerizawaI.IwasakiN.IshidaH.SaitoS

But more studies are needed to understand the finding

However, the timeline to meaningful weight loss may surprise you