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This improvement in exercise capacity can lead to more effective workouts, which in turn can contribute to increased fat loss and muscle gain over time

It is characterized by high hospital costs, morbidity, and mortality, and it provokes a high hospitalization rate and inpatient mortality [376,377,378]

However, the convergence of outcomes between the treatment groups after 5 years was significant, and a large loss of patients to follow-up is suspected to have biased the treatment effect calculations

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