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Key properties: Strong appetite stimulation the most pronounced of any GHRP (can be a benefit or drawback) Moderate cortisol increase higher than GHRP-2 Good GH release effective but not as potent per mcg as GHRP-2 Strongest ghrelin mimicry most activation of non-GH ghrelin pathways GHRP-6 is studied when appetite stimulation is a desired effect (e.g., recovery from illness, muscle gain phases) alongside GH release

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Some need more aggressive interventions to improve metabolic health

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This potential is most likely to be realized when GLP-1 RA based therapies are embedded within structured, stepped-care frameworks that integrate nutritional, psychological, and social dimensions