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IDO1 inhibitors have been tested in a variety of anti-cancer treatments, including epacadostat (Table 1), indoximod, and navoximod, but compared with the results of preclinical trials, the efficacy of IDO1 inhibitors alone have not been objectively reflected in the clinical trials (Soliman et al., 2016

To identify these regulators, we conducted immunoprecipitation-coupled mass spectrometry (IP-MS) and identified an alternative ORF (alt-ORF) C11ORF98 -encoded microprotein (herein named RSMC, 28S rRNA/ribosome and Sororin micro-cofactor) as a Sororin partner in human cells

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The expression of antioxidant genes regulates H 2 O 2 /O level in stem cell metabolism, thereby preserving their pluripotency [280]