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And if its a SIBO thing, which I actually think is becoming more and more prevalent, that tends to be a stress issue [00:20:00] to where you need to just take your time

Excess Fe 2+ catalyzes the production of hydroxyl radicals (OH) through the Fenton reaction, thus triggering a chain reaction of lipid peroxidation ( ACSL4 ) and lysophosphatidylcholine acyltransferase 3 ( LPCAT3 ), promotes the enrichment and remodeling of polyunsaturated fatty acids (PUFAs) in membrane phospholipids ( GPX4 glutathione (GSH) antioxidant system will damage the detoxification of lipid hydroperoxides, resulting in the fatal accumulation of lipid peroxidation products ( 2.2 Pathological mechanisms in DKD In DKD, the susceptibility to ferroptosis is jointly driven by iron metabolism disorder, impaired antioxidant defenses, and enhanced lipid peroxidation (Figure 1)

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