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The approach combines hypotonicity and thermosensitive gel-forming polymers (e.g., Pluronic F127) formulated below their critical gel concentration (CGC), allowing for rapid and uniform water absorption-driven spreading over the ocular surface

TDP-43 pathology is one of the common proteinopathies observed in a large spectrum of ALS patients, including familial, sporadic and ALS with frontotemporal lobar dementia (ALS/FTLD) 6,7,8,9

Organ-on-chip: advancing nutraceutical testing for improved health outcomes

Individual variation exists

Using all three together requires precision to avoid GH receptor desensitization or excessive IGF-1 levels