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Maternal low-dose caffeine intake during the perinatal period promotes short- and long-term sex-dependent hormonal and behavior changes in the offspring

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2.5.4 Urine sample preparation Aliquots (30 L of urine, 50 L of 50% methanol aqueous solution, 50 L of IS solution (1,500 ng/mL, dissolved in acetonitrile), and 300 L of acetonitrile) were added to EP tubes

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The medication increases photosensitivity by 30-50%, making skin burn faster even with brief sun exposure, requiring SPF 30+ sunscreen reapplication every 2 hours

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Koide et al., 1999

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