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the purpose of elongating the N-terminal acyl group and removing the N-terminal amino group was to increase the probability that resultant molecules might be BBB permeable and access the brain parenchyma

GLP-1RA as an independent class of drug is also noteworthy in reduction of weight in patients with and without poor glycaemic control with multiple trials backing the efficacy of agents including semaglutide and liraglutide (116)

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