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With inflammation being tightly regulated by NF-B and STAT3 pathways, GLP-1 RAs have been shown to inhibit NF-B and reduce the generation of inflammatory mediators, among other inflammatory cytokines, reactive oxygen species, adhesion molecules, and chemokines [18,19,29]

Eine Ausnahme bildet Tirzepatid: Der Wirkstoff ahmt nicht nur GLP-1, sondern auch GIP nach, ein weiteres Darmhormon

Eur J Pharmacol 764:562570 Demontis F, Serra F, Serra G (2016) Antidepressant-induced dopamine receptor dysregulation: a valid animal model of manic-depressive illness

For this, we need to take a deeper look

Some studies show no change in GSH status upon supplementation of oral glutathione (reduced form) in healthy subjects