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[3] These include poor growth, apathy, having no desire for food, and developmental regression

Peer review Peer review information Nature Medicine thanks Christiana Kartsonaki, Peter Rossing, Naveed Sattar and Vikas Sridhar for their contribution to the peer review of this work

Red flags Warning signs suggesting vendor problems include no available testing documentation, prices dramatically below market rates, poor packaging or unprofessional presentation, no customer service response, and claims that seem too good to be true

But the peptide therapies being touted online for their wellness and longevity benefits have not undergone large-scale, rigorous clinical trials involving humans

Preclinical studies demonstrated that AOD-9604 was generally safe after chronic oral application in rats and cynomolgus monkeys, with no genotoxic concerns identified