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Studies indicate that A1AT therapy can lead to a reduction in systemic inflammation, as measured by lower CRP levels, thus potentially decreasing the overall inflammatory burden on the lungs (68) Moreover, the reduction in inflammatory markers can also be indicative of the therapys effectiveness in mitigating the proteolytic damage caused by neutrophil elastase, which is typically unopposed in AATD patients due to low A1AT levels

Hypertension 73, 671679

10.1016/j.cell.2017.11.048 Cell 41 ItohT.FairallL.AminK.InabaY.SzantoA.BalintB

Mice with OVA-induced asthma were treated with 30 or 50 mg/kg pterostilbene and lungs were investigated for airway inflammation [206]

This article covers the pharmacology of both compounds, what glutathione actually does in the body versus what it's marketed to do, and the specific scenarios where combining them might make clinical sense