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82 The analysis of B-complex vitamins relationship to hair follicle metabolism reveals that out of the eight water-soluble B vitamins essential for cellular function, only four compounds - riboflavin (B2), biotin (B7), folate, and cobalamin (B12) - demonstrate a clinically significant correlation with hair loss pathophysiology

Fu X, et al

In the specific case of cysteine-deprived cell death, lipid peroxidation acquires a character of chain-reaction due to the Fenton reaction with ferrous iron (Fe 2+ )

The increased Bax/Bcl-2 ratio promotes mitochondrial outer membrane permeabilization and cytochrome c release, leading to the activation of caspase-9 and downstream executioner caspase-3 (78)

J.MacgregorC