Despite their rarity, they exhibit a substantial mortality rate, contributing to about 34% of cancer-related fatalities each year [1]
doi: 10.1016/j.jep.2024.118209 72 NerildHHGilliam-VighHEllegaardA-MFormanJLVilsbllTSonneDPet al
GLP-1 medications also carry some serious (but rare) warnings: Potential risk of thyroid C-cell tumors (observed in rodent studies, unclear relevance in humans) Risk of gallbladder problems Pancreatitis (rare but documented) Hair loss (temporary, related to rapid weight loss rather than the drug itself) One notable advantage of GLP-1 medications: they do not cause cognitive dysfunction, do not carry teratogenicity warnings as severe as topiramate, and are not controlled substances
Cell Res 26 , 320335 (2016)
It is important to be aware of potential side effects, the most common are: The most frequently encountered side effect of bremelanotide is nausea (40.0%), which may be intolerable to some people Flushing (20.3%) Injection site reactions (13.2%) Headache (11.3%) Vomiting (4.8%) Who is a good candidate for PT-141