glp 1 muscle mass loss 1/2) New research suggests GLP-1 weight drugs probably do NOT cause disproportionate loss of functional lean muscle. The confusion has arisen from the fact that DXA scans capture and pool a GLP-1 drugs for weight loss:

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Bordeaux and ANR (Grant ANR-15-CE07-0010) is also gratefully acknowledged

What theyre saying: We believe that inhibiting new pathways on top of GLP-1 receptor agonism has the potential to achieve comparable overall reductions in body weight, but with improved quality of a weight loss, resulting in more fat loss while preserving or actually increasing muscle mass. Regenerons CSO George Yancopoulos The big picture If any of these medications (or combinations of medications) can actually enable people to lose weight while preserving muscle mass, the impact on public health could be huge but itll likely be years before they reach the market

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The biggest example of this trend was seen back in March, when semaglutidea GLP-1 agonist sold by Novo Nordisk under the brand name Wegovygained FDA approval to reduce the risk of major adverse cardiovascular events in overweight or obese patients with cardiovascular disease