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ABSTRACT The use of the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist tirzepatide has markedly increased for the treatment of weight loss and management of diabetes mellitus

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Less common but documented adverse events include pancreatitis, gallbladder disease (cholelithiasis and cholecystitis), and acute kidney injury related to dehydration from severe nausea or vomiting

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