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2.1.1 System Xc - Solute carrier family 7 member 11 (SLC7A11, catalytic subunit) and solute carrier family 3 member 2 (SLC3A2, regulatory subunit) make up System Xc- ( The antioxidant response is mediated by NRF 2, a master transcription factor

Our analysis defines the dimer interface in the resting and activated state, indicates how ligand binding is coupled to gating, and suggests modes of dimerdimer interaction in the assembled tetramer

Front Immunol 2020, 11: 1416

Unraveling the potential role of glutathione in multiple forms of cell death in cancer therapy