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Changes in gut barrier permeability can expose the host to microbial components that amplify low-grade inflammation, ultimately reducing the sensitivity of enteroendocrine signaling pathways such as GLP-1

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There may also be a novel non-enzymatic effect of GSTP, which plays an important role in the regulation of the classical ER signaling pathway by modification of transcriptional cofactors, such as receptor interacting protein 140 (163)

Estudios en modelos animales sugieren efectos ansiolticos y antidepresivos, posiblemente mediados por la interaccin con los sistemas dopaminrgico y serotoninrgico

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