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The most serious side effects include gastroparesis (stomach paralysis), bowel obstruction or ileus requiring surgery, intestinal blockage, gallbladder disease, vision loss including NAION (non-arteritic anterior ischemic optic neuropathy and arteritic anterior ischemic optic neuropathy), sudden vision loss or blindness, deep vein thrombosis (blood clots), severe malnutrition, and organ damage from prolonged gastrointestinal injuries

Keep in mind that blood sugars can spike intermittently, so its important to keep an eye on them

Over time, this helps reduce the appearance of pigmentation and contributes to a brighter, more refreshed complexion

Mitochondrial reactive oxygen species cause major oxidative mitochondrial DNA damages and repair pathways

[9] However, the authors acknowledged significant limitations, including risk of bias, small sample sizes, and considerable heterogeneity across studies