The GLP-1 receptor agonist liraglutide reverses mania-like alterations and memory deficits induced by d-amphetamine and augments lithium effects in mice: relevance for bipolar disorder
They developed at the intersection of healthcare system limits, telehealth expansion, How Does GLP-1 Telehealth Fit Into Modern Weight Management
Since then, a number of triple agonists have entered clinical development, with one in phase three clinical studies but have yet to reach the market (Capozzi, DiMarchi, Tschp)
48,49 Heart Rate Increase GLP-1RAs are known to cause a modest, dose-dependent increase in resting heart rate
What we are seeing now is their additional benefit for treating obesity as a metabolic disease, not just a number on the scale