Drugs in development include phosphodiesterase-4 inhibitors, p38 mitogen-activated-protein-kinase inhibitors, and NF-B inhibitors
The generation of these ROS within the phagocytic complexes of macrophages and neutrophils is the means by which these cells degrade phagocytosed microorganisms
Carey, Simmons University, United States Reviewed by Jong-Sang Kim, Kyungpook National University, Republic of Korea Franziska S
In pregnant women, periodontitis induces synergistic changes in their microbial profiles via the oral-gut axis, with positive correlations between oral pathogens and specific gut bacteria such as Coprococcus , alongside competitive interactions with other gut genera like Lachnoclostridium , collectively reshaping the maternal microbial ecosystem network (Cheng et al., 2024)
[DOI] [PubMed] [Google Scholar] 189.Li XY