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Besides a diagnosis of NF1, the other primary known risk factor for MPNST development is radiation exposure, typically in the context of a secondary malignant neoplasm occurring following radiotherapy [22]

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doi:10.1016/j.ijporl.2012.11.037

These may include: Nausea and stomach upset Diarrhea Constipation Injection site redness or swelling Itching Headache Dizziness Blood clots Swelling In rare cases, some people may experience an allergic reaction to vitamin B12, which can cause symptoms such as hives, difficulty breathing, and swelling of the face, lips, tongue, or throat

Locally produced xenin and the neurotensinergic system in pancreatic islet function and beta-cell survival